Saturday, June 11, 2022

15 Years and Healthy

Don Porter 9-14-2014 - Intro to Telomere lengthening for health/extended longevity with THERACURMIN® Drs. in India call it the “all in one solution.” Their “all in one solution” is curcumin. Why would medical professionals describe curcumin with such a powerful statement? Could it really be so powerful that it truly is the “all in one solution”? I have researched herbs and nutrition for 30+ years. Last 8 years have gotten serious, developed good knowledge of many of the top medicinal plants in the world. However, several years ago came across a number of studies on curcumin from different scien¬tific institutions in various parts of the world - especially in Japan. In all, identified 2,000+ studies conducted on Curcumin over the last several years, and as many as a dozen new studies every month - a first in my experiences ! My curiosity went into overdrive - why has this plant intrigued so many scientists? This large amount of research is a clue that scientists are seeing a tremendous medici¬nal benefit of curcumin. This really intrigued me, and while not having a specific technical background, I have a passion for R&D combined with Due Diligence of high quality Healing/Curing medicinal products. Initiated serious searching with healers scientists around the world to inquire as to what they were discovering and why there was this huge influx of scientific research. Eventually, my internet digging identified scientists @ a conference in India on curcumin. What I discovered was amazing. 30+ years looking @ health food industry - alternative medicine, I never thought I would have the opportunity to see a plant with such medicinal benefits, even extending Telemere length Enhacing the Benefits of Curcumin - Many studies show curcumin has serious benefits, major issue limiting its clinical use has been that it is not very well absorbed. Several types of curcumin products have now been developed (BCM -95 + others) to more effectively raise blood and tissue levels of curcumin. THERACURMIN®, by THERAVALUES Corp. is by far the most advanced of these techniques. This all-natural preparation reduces the particle size of curcumin, while dramatically increasing its solubility. The average particle size of typical curcumin is 22.75 μm. In Theracurmin, the particle size has been reduced to 0.19 to 0.3 μm—a reduction of over 100X This reduced particle size curcumin is then mixed with natural emulsifiers to suspend it in a highly bioavailable mixture that is then dried. This Photo showing the IMPRESSIVE dissolution of Theracurmin in water compared to regular curcumin powder.on left. This dramatic dispersion in water translates to the dramatic increases in bioavailability seen with THERACURMIN®, by THERAVALUES Corp. -2- THERACURMIN® Increases “Free” Curcumin - In addition to being poorly absorbed, regular curcumin is rapidly metabolized in the liver. When measuring levels of curcumin in the blood during absorption studies, the value of curcumin is based upon total curcuminoids, including metabolites. The only product form that has shown to actually increase the free curcumin form is Theracurmin. Since free curcumin is significantly more active than the metabolites, it appears highly likely that Theracurmin is not only better absorbed, but it also produces additional benefits as compared to other supplemental forms of curcumin. Health Benefits of Theracurmin - Because Theracurmin enhances the absorption of curcumin, all of the benefits associated with curcumin are also enhanced. Theracurmin has been the subject of Many impressive clinical studies that have shown Theracurmin possesses an ability to reduce tissue damage caused by inflammation, improve liver function, increase the ability of the heart to function more efficiently, and increase the flexibility of the arteries. Currently, Theracurmin is being investigated for additional properties at some of the major universities and research centers in the world. The dosage recommendation of Theracurmin, based upon the existing clinical evaluation, is 300 to 600 mg per day. THERACURMIN® is the Most Bioavailable Form of Curcumin - Having now reviewed many graphs, charts, videos, medical school results: Clinical Research Institute-National Hospital, Organization Kyoto Medical Center, Columbia-Dept of System Chemotherapy and Molecular Sciences, Division of Bioinformatics and Chemical Genomics, Alzheimer’s prevention at the UCLA Longevity Ctr, Graduate School of Pharmaceutical Sciences-Kyoto Univ, including data from, Div. of Molecular Medicine, School of Pharmaceutical Sciences, Univ of Shizuoka, Outpatient Oncology Unit, Kyoto Univ Hospital, Faculty of Health and Sport Sciences, Univ of Tsukuba, The Univ. of Texas MD Anderson Cancer Center, and THERAVALUES Corp this demonstrates Theracurmin is by far the most bioavailable form of curcumin. Theracurmin is the only curcumin preparation currently available that produces a clear dose response. What that means is that even small dosages of Theracurmin increase blood measurements of curcumin, and, as the dosage increases, so does the blood level. This increase is linear, meaning that it increases in the blood in a parallel fashion to the dosage. This absorption profile is extremely important; as the effectiveness of curcumin within the body requires achieving effective concentrations. Theracurmin is able to achieve necessary concentrations within the body that are not likely to be easily achieved, if at all, with other curcumin preparations. A Few Key Bullet points of. THERACURMIN® : • 2,000 studies conducted on curcumin last several years, a dozen new studies every month • Curcumin effective any kind of inflam¬mation cause of 80% of diseases – heart disease, obesity, arthritis osteo-rheumatoid, bursitis, bronchitis, lupus, sinusitis, asthma, fibromyalgia-migraine headaches, hypertension, gall stones, MS, asthma, Indicates THERACURMIN® heal¬ing benefits top of plant medicines-Organic - unheated Aloe also • Major Studies - THERACURMIN is the 1st nanoparticle formulation of curcumin that demonstrates improved bioavailability in human subjects. This compound could be a promising tool when testing the potential anticancer effects of curcumin in clinical trials. THERACURMIN absorption found to be more than 40X higher than that of curcumin powder in rats. Healthy human volunteers were administered orally 30 mg of THERACURMIN or curcumin powder. The Absorption of THERACURMIN was 27X higher than that of curcumin powder. In addition, THERACURMIN exhibited an inhibitory action against alcohol intoxication after drinking in humans, as evidenced by the reduced acetaldehyde concentration of the blood. These findings demonstrate that THERACURMIN shows a much higher bioavailability than currently available preparations -3- Pharmacy News March 25, 2012 by Rx Times Leave a Comment Theravalues: Extensive Clinical Trials Affirms the Benefits of Theracurmin™ on Diastolic Function in Hypertensive Patients CHICAGO–(BUS. WIRE)–Theracurmin, an absorption-enhanced form of curcumin, developed by Theravalues Corp., a Japanese bio-venture, is affirmed to be beneficial on diastolic function in hypertensive patients. American College of Cardiology Poster Abstract Shows Standard Lipid Profile Inaccurate for LDL Cholesterol Below 70 mg/dL CHICAGO–(BUSINESS WIRE)–Science presented today at the American College of Cardiology’s 61st Annual Scientific Sessions in Chicago reveals the importance of directly measured lipoprotein cholesterol levels. New Data Suggests Results of PLATO Genetic Sub-Study Outcomes for BRILINTA® (Ticagrelor) Not Driven by Poor Metabolizers of Clopidogrel CHICAGO–(BUSINESS WIRE)–AstraZeneca (NYSE: AZN) today announced results from a sub-analysis of the PLATO genetic sub-study that evaluated the impact of poor metabolizers of clopidogrel. Data suggests results were consistent with the overall outcome of the PLATO study, with BRILINTA (ticagrelor) compared to clopidogrel, even after poor clopidogrel metabolizers were excluded. Results of this sub-analysis were presented today at the American College of Cardiology Scientific Sessions (ACC), in Chi New Data Suggests BRILINTA® (ticagrelor) Reduced First and Recurrent Cardiovascular and Ischemic Events CHICAGO–(BUSINESS WIRE)–AstraZeneca (NYSE: AZN) today announced new data from a sub-analysis of the PLATO study that suggests that BRILINTA® (ticagrelor) tablets resulted in a reduction in hazard for time to first events, recurrent cardiovascular (CV) and ischemic events, when compared to clopidogrel. These data were presented today by Dr. Payal Kohli of the TIMI Study Group and Brigham and Women’s Hospital, at the American College of Cardiology Scientific Sessions (ACC), in Chicago, Ill. “The - See more at: http://www.rxtimes.com/pharmacy-news-10/#sthash.UxUy2cg1.dpuf -4- Are Telomeres The Key To Aging And Cancer? Inside the nucleus of a cell, our genes are arranged along twisted, double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are stretches of DNA called telomeres, which protect our genetic data, make it possible for cells to divide, and hold some secrets to how we age and get cancer.Telomeres have been compared with the plastic tips on shoelaces, because they keep chromosome ends from fraying and sticking to each other, which would destroy or scramble an organism's genetic information. Yet, each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide; it becomes inactive or "senescent" or it dies. This shortening process is associated with aging, cancer, and a higher risk of death. So telomeres also have been compared with a bomb fuse. I never thought I would have the opportunity to see a plant with such medicinal benefits, even extending Telemere length as THERACURMIN® apparently can ! ------------------------ JETRO RIT Programme: Hokkaido BioIndustrial Exchange The Hokkaido Ministry of Economy Trade & Industry (METI) together with the Hokkaido Bio Industrial Cluster Forum, are engaging with Natural Products New Zealand, in a program of Industrial Exchange.On 15th Oct 2009, 13 Hokkaido companies and 9 New Zealand companies participated in the Health Ingredients Japan Trade Show (Tokyo Big Sight). Business talks were held (20 meetings). Following this, 5 New Zealand participants were invited to Sapporo, from 22nd - 24th February 2010, in order to promote long-term market enlargement, the formation of new alliances and technology exchange. Participating enterprises had the opportunity to introduce their respective companies through poster presentations and pamphlets showcasing their products and technologies. In addition, companies delivered presentations highlighting their key technologies and selling points and to indicate desired areas of collaboration and partnering opportunities. After the reception, further networking over dinner provided opportunity to deepen business relationships. Companies involved in the programme are listed below: Theravalues -Contract research provider for researchers and industry, including Analysis Service for Nuclear Receptors Nuclear receptors (intracellular proteins, that migrate into the nucleus to regulate the transcription of survival-related genes when bound to vitamins, hormones, fatty acids, etc.) 48 kinds of nuclear receptors are known to exist in humans and are reported to be involved in diabetes, arteriosclerosis, obesity, osteoporosis, insomnia, and carcinogenesis. They are also known to be the drug targets for hyperglycemia and hyperlipemia. Theravalues offer services for reporter gene assays to test the activation of nuclear receptors. They are developing a range of functional materials in collaboration with leading universities and research institutes, developing formulation techniques, and focusing on the development of new value chains for functional materials. Research interests include: Curucmin DDS, Nuclear receptor activation materials, Thioredoxin, Xanthines, and activation of human transcription factors involved anti-cancer, antiviral, detoxification and immunoactivation, by Bamboo grass extract. Carol Greider, molecular biologist at Johns Hopkins University, says understanding the caps on the ends of chromosomes may soon translate to understanding cancer, lung diseases, and even normal aging,